您现在的位置: 论文网 >> 医药学论文 >> 医学论文 >> 乳腺黏液腺癌与纤维腺瘤的MRI诊断研究论文

    乳腺黏液腺癌与纤维腺瘤的MRI诊断研究

    出处:论文网
    时间:2019-09-11

    乳腺黏液腺癌与纤维腺瘤的MRI诊断研究

      【中图分类号】R445. 2 【文献标识码】A 【文章编号】1005-0019(2019)15--01

      乳腺粘液腺瘤发病率较低,临床数据显示其占乳腺癌的1%-6%,具有大量细胞外粘液成分,按照细胞外粘液含量可分为单纯粘液腺瘤以及混合性粘液腺瘤。该肿瘤临床表现以及影像学图像均无典型性,容易与纤维腺瘤混合,造成误诊。MRI为一种无创诊断方式,应用乳腺线圈和各种扫描序列可进行多方位检查,根据以上情况本次重点分析MRI诊断乳腺黏液腺癌与纤维腺瘤表现的差异,为提高后续临床诊断率提供依据。

      1 资料与方法

      1.1 一般资料 2017年1月至2018年12月 期间在我院接受治疗的经手术病理证实的7例(8病灶)乳腺粘液腺癌患者以及11例(13病灶)纤维腺癌患者。乳腺粘液腺癌患者年龄22-51岁,平均(36.5±2.3)岁,纤维腺癌患者年龄22-56岁,平均(38.0±2.9)岁,比较分析两组患者一般资料差异不显著(P>0.05),患者均用以本次检查方法并签订相关协议。

      1.2 方法 GE Excite HD 1.5T MRI扫描仪。叮嘱患者取仰卧位,双侧乳房自然下垂于线圈内。扫描序列及参数:(1)矢状面脂肪抑制FSE T2W 扫描,TR3140-4640ms,TE81-85ms,5.0mm层厚,1.0mm间距;轴位:SE-EPI DWI 扫描,b值为0.8s/mm2,TR为5000-6000ms,TEwei 62-71ms,6.0mm层厚,1.5mm间距;轴位脂肪抑制GRE T1W扫描:TR为6ms,TE为3ms,T1为13ms,FA为10°,3.2mm层厚,层间距为0。轴位脂肪抑制T1W多时相动态增强扫描:TR为6ms,TE为3ms,T1为13ms,FA为10°,3.2mm层厚,层间距为0,对比剂为Gd-DTPA,剂量为15ml,时相为8。

      1.3 图像处理 按照ACR BI-RAD MRI标准写诊断报告书,并强调病灶点状、肿块型强化、非肿块型强化分类。肿块病灶需要描述形态、边缘以及内部强化情况;非肿块型需要按照分布以及内部强化描述,记录T2以及T1特征。工作站利用Functool 软件进行动态增强曲线以及表现扩展系数(apparent diffusion coefficient,ADC)测量,评分测量三次取最小值。图像由两名经验丰富影像学专家阅读,意见不合时由第三名医师加入。

      1.4 数据分析 结果中符合正太分布的计量资料使用(均数±标准差)表示,并以t检验分析,P值(双侧)<0.05时表示差异具有统计学意义。

      2 结果

      2.1 形态学特征 乳腺粘液腺癌7例患者中,中6例单发,1例多发;纤维腺瘤11例患者中,6例单发,5例多发。粘液腺癌形态:3个病灶为圆形,2个病灶为浅分叶状,3个为不规则;2病灶边缘光滑,6病灶边缘毛糙。纤维腺瘤5个病灶为圆形,3个病灶为浅分叶状,3个为不规则;4病灶边缘光滑,7病灶边缘毛糙。

      2.2 ADC值比较 粘液腺癌患者ADC值为(2.13±0.35)*10-3mm2/s;纤维腺瘤患者为(1.01±0.30)*10-3mm2/s,两组患者ADC值差异具有统计学意义(t=3.06,P=0.041)。

      2.3 动态增强扫描曲线特征

      粘液腺瘤患者3个病灶呈环形强化,并逐渐具有填充趋势,5病灶不均匀强化,4个病灶呈Ⅰ型,2个病灶呈Ⅱ,2个呈Ⅲ型。纤维腺瘤8病灶为均匀强化,3病灶为不均匀分隔强化;10个病灶呈Ⅰ型,3个病灶呈Ⅱ型。

      3 讨论

      乳腺粘液腺癌属于特殊类型的浸润性癌症,可分为单纯性和混合型,临床一般以单纯型常见,其临床特征以及影像学情况均与纤维腺瘤具有较大相似性。本次对两种疾病分析进行MRI诊断,结果显示两组形态学具有交叉重叠,比较难以根据形态学区分。增强扫描后,两种肿瘤均表现为流入型的曲线,病灶主要以逐渐强化为主,差异无统计学意义。粘液腺癌患者ADC值为(2.13±0.35)*10-3mm2/s;纤维腺瘤患者为(1.01±0.30)*10-3mm2/s,具有差异。粘液腺癌ADC值明显高于纤维腺瘤,主要为乳腺粘液腺癌含有较多粘液成分,粘液一般为大分子以及中等分子物質,含水量较低,因此不具备水分子弥散受限物理基础,使得ADC值升高。总之,经对比分析我们认为:粘液腺瘤和纤维腺瘤MRI表现具有重叠,但ADC值具有明显差异,可根据该项进行鉴别。

    乳腺黏液腺癌与纤维腺瘤的MRI诊断研究

    论文搜索
    关键字:腺瘤 黏液 腺癌 乳腺 纤维 研究
    最新医学论文
    针灸临床带教中的几点体会和思考
    高职院校对医学生人文素养培养的思考
    乳腺黏液腺癌与纤维腺瘤的MRI诊断研究
    浅谈功能性消化不良
    加味柴胡疏肝散对肝郁气滞型功能性消化不良
    小儿隐匿性阴茎的诊治体会
    胰腺实性-假乳头状瘤应用多层螺旋CT诊断的效
    早产炎性病因的进展研究
    张恒龙教授外科治疗糖尿病足经验
    H型高血压的研究现状及进展
    热门医学论文
    不同情况下病人的心理护理
    Caspase ,BCL-2蛋白家族与细胞凋亡调控机制
    传染病的预防措施
    高血压与X综合症
    慢性疲劳综合征与体育锻炼
    中医哲学和中医学及中国生命科学
    吸烟与眼部疾病
    儿童溃疡病诱发因素分析及护理对策
    抗菌肽的研究进展
    军团菌病的研究进展
    分分快三app

    hg792.com | 3534k.com | www.8473g.com | 444000r.com | www.2078f.com | www.895594.com | 7508m.com | www.7681002.com | 721023.com | www.C63.COM? | 3404e.cc | www.472709.com | am56.cc | www.635444.com | www.111307.com | www.ab678.com | www.zcwf1.com | 8905s.com | www.78949r.com | 61653r.com | www.334175.com | 0099066.com | www.65066cc.com | sjxche.com | www.998762.com | 635120.com | www.xy5050.com | www.73736a.com | www.99927nn.com | www.546669.com | www.32126r.net | www.854242.com | www.81866c.com | www.999hy.cc | www.yddc02.com | www.745568.com | www.323006.com | www.755903.com | www.z0888.com | www.799100.com | www.22799.com | www.516105.com | www.g30226.com | www.129029.com | www.6834j.com | 667766g.com | www.37337.com | 97297t.com | www.103111.com | xh99.pw | www.65066bb.com | b4116.com | www.8905e.com | 7240p.com | www.js02348.com | swin6.com | www.3479b.com | 00064066.com | www.203552.com | www.3959h.com | 5003ll.com | www.eb000.com | yinhe100.cc | www.30350z.com | 5856oo.com | www.2655268.com | 2997704.com | www.hf5885.com | www.hg3636.com | 666ths.com | www.c44xx.com | 4379d.com | www.773560.com | x33a.vip | www.599643.com | www.bet3651214.com | c388o.com | www.690510.com | 3614f.com | www.66332f.com | www.0686222.com | www.344242.com | www.kj4949.com | 364982.com | www.266820.com | 3156rrr.com | www.625069.com | www.9699.us | 19880.com | www.780sun.com | 2247q.com | www.401276.com | www.76775a.com | 39199n.com | www.6768996.com | 88y66.vip | www.234259.com | www.pj928.com | blr8844.com | www.49956z.com | www.7830j.com | blr7033.com | www.168a56.com | 76678.com | www.33112v.com | www.829797b.com | 9569822.com | www.987580.com | www.45625.com | 4546.com | www.hx1112.com | www.302848.com | boyingyule.com | www.34788l.com | www.o8867.com | ule610.com | www.4323q.com | www.pj39330.com | 3225j.com | www.120782.com | www.www-36525h.com | baihu188.com | www.21202n.com | www.16297733.com | 9506c.com | www.929115.com | www.37111m.com | 063939.com | www.763829.com | www.33c668.com | 2096u.com | www.150882.com | www.1559508.com | kk76669.com | 89777j.com | www.37266m.com | www.mmtx22.com | 3522p.vip | www.3126t.com | www.000084.com | js551.com | www.375736.com | www.0096ff.com | 15f9.net | 11772007.com | www.560721.com | www.15365e.com | 6245f.com | 5622f.com | www.83033t.com | www.hg833.com | 7811o.com | 6647d.com | www.hg0298.com | www.yl66636.com | 1468ccc.com | www.711893.com | www.4996nj.com | www.e26055.vip | 3807vv.com | www.hy5509.com | www.38345c.com | www.6033d.com | 1017v.com | www.919709.com | www.q80288.com | www.hgcn888.com | 8569811j.com | sha162.com | www.906777.com | www.457777.com | weid.tv | 3511.sbf822.com | www.9928d.com | www.668cp55.com | 38989b.com | 1966xpj.com | www.628846.com | www.56011n.com | www.hg246.com | 5856r.com | kk3189.com | www.6611f.cc | www.982935.com | www.330099u.com | r99345.am | www.431770.com | www.0343i.com | www.88854.com | 64111y.com | ii00558.com | www.186796.com | www.919699.com | www.uc.cc | www.hg3733.com | ff38648.com | 1669n.com | www.609812.com | www.6678579.com | www.1299js.com | www.hg298.com | 4369.com | 131ww.net | www.541522.com | www.68203dd.com | www.170676.com | www.76543e.com | 777k7.com | 1489p.com | www.112819.com | www.16878h.com | www.377666v.com | www.vnsr22888.com | www.g67783.com | 66671h.com | 3030011.com | www.197802.com | www.25688g.com | www.ee00668.com | www.hg7857.com | www.223456r.com | 8988r.com | u8381.com | 3178p.com | www.558429.com | www.66332d.com | www.7036d.com | www.kzcs4.com | www.67797a.com | 3379aa.com | 4465p.com | bet3659098.com | www7893.cc | www.606684.com | www.32123r.com | www.12345606.cc | www.7415nn.com | www.04080.com | www.365815n.com | zzc222.com | 899523.com | 0500.com | 5858394.com | xpj86.com | haianw.com | www.640118.com | www.36788r.com | www.415977.com | www.xj7005.com | www.752568.com | www.160345.com | www.fh6000.com | www.fh6666.com | 588.cc | 7742l.com | 20053377.com | lh66d.com | 79889a.com | 78112211.com | 939000.com | 500000557.com | www.040416.com | www.599091.com | www.c5235.com | www.9356x.com | www.725602.com | www.3775v.com | www.38775bb.com | www.38138a.com | www.99113q.com | www.998855q.com | www.bg5858.com | www.tm228.com | www.765543.com | www.pj5767.com | www.362844.com | www.3643u.com | www.83hg.com | www.58777l.com | www.7025j.com | www.gd68.com | www.3056008.com | www.22751.com | www.87680k.com | www.3332hg.com | www.10899a.com | www.boma0150.com | www.3506s.com | www.774167.com | www.hg418.com | www.367888a.com | www.hg88996.com | www.884477.com | www.js421.com | www.567711.com | www.ylc366.com | www.01885d.com | www.3846l.com | www.4972u.com | www.38138t.com | www.33678bb.com | www.hgbet1.com | www.436bbb.com | www.130057.com | www.53900q.com | www.hw52.com | www.336779.com | 68680029.com | 8381ss.com | ibook8.com | 3242o.com | hwcp4444.com | www.sjs14.com | www.vns9948.com | www.v99950.com | www.767666.com | www.8967q.com | www.733484.com | www.8582ww.com | www.16878w.com | www.903079.com | www.069961.com | 51200xx.com | zhcp69.com | 4577.com | 2851f.com | www.3615004.com | www.3844d.com | www.hao500.com | www.535083.com | www.81520m.com | www.944229.com | www.rcw321.com | 3mgmmmm.com | 6002g.com | 官网捕鱼3.com | www.hg148.com | www.242365.com | www.58665r.com | www.288582.com | www.29277m.com | www.586775.com | 4632299.com | pj600600.com | 500000515.com | www.76060y.com | www.hg8562.com | www.b35jj.com | www.85330.com | www.987428.com | y86811.com | x33k.vip | 3242.am | www.kelake77.com | www.b35pp.com | www.176.ag | www.681048.com | 3078p.com | 65365.com | 5855.com | www.cq0066.com | www.blr3344.com | www.an966.com | 53166i.com | 5219k.com | 88905151.com | www.822620.com | www.8577b.cc | www.810852.com | 3522tt.cc | 15856s.com | www.yh2198.com | www.58665c.com | www.1432Z.COM | www.269913.com | 7599xx.com | 2851a.com | www.tyc1802.com | www.p32031.com | www.082wy.com | 3413366.com | 67890tt.com | www.10899d.com | www.00772z.com | www.5522m.cc | 033b.net | 2677fff.com | www.www-50007000.com | www.518pj.com | qhbwz.com | 9659z.com | www.lb0011.com | www.4446fff.com | www.2350g.com | d3410.com | fc9559.com | www.hg8247.com | www.424277.com | www.259989.com | rr444000.com | www.vns343.com | www.44118e.com | www.618393.com | dz0777.com | www.44466638.com | www.704905.com | www.771245.com | 55545q.com | www.3657z.com | www.47506e.com | www.609713.com | 86811aa.com | www.4107c.com | www.ba509.com | www.377192.com | 2214jj.com | www.hg00111.com | www.1232222.net | xpj6602.com | 6261pp.com | www.02110.com | www.50051j.com | hb56138.com | www.058hx.com | www.xpj778888.com | www.602430.com | 4461t.com | www.pj66615.com | www.7714h.com | so11111.cc | 86688004.com | www.07679t.com | www.41518c.com | 80850dd.com | www.23636.com | www.807839.com | 3559hhhh.com | www.822620.com | www.022l.cc | 3936k.com | www.82894w.com | www.62118d.com | 365611.com | www.900671.com | www.162323.com | aa7742.com | www.995t.net | www.89894p.com | 1077.cc | www.88807l.com | www.c773776.com | 2477000.com | www.3643t.com | www.83033x.com | 55663885.com | www.hg9930.com | www.00czj.com | 3890p.com | www.hg068008.com | www.455518.com | 8557a.com | www.v80288.com | 11018l.com | www.8520q.com | www.62778811.com | 7811zz.com | www.js60a.com | www.bang | h51335.net | www.3157n.com | 888.tf | www.5009844.com | www.4988c.cc | 0080u.com | www.hg8423.com | www.609717.com | 2373d.com | www.2848.com | 15a42.net | www.n9163.com | www.709812.com | wns6.net | www.3398788.com | 3616q.com | www.hg995.com | www.547377.com | 2418009.com | www.993916.com | tzvip2020.com | www.0816msc.com | www.187517.com | www.hg9951.com | www.68689w.com | 3640.vip | www.z32031.com | 47479.com | www.103111.com | www.095005.com | www.hg2218.com | www.7793n.com | 2127h.com | www.280sun.com | 8036ocom | www.4078h.com | 3467t.com | www.tqdc222.com | www.186769.com | www.he0066.com | www.w408.com | 2247s.com | www.66653g.com | 777659111.com | www.52062c.com | 43234323.com | www.b35ff.com | 55984q.com | www.24264m.com | 2012vip77.com | www.xpj29666.com | www.178612.com | www.995q.net | www.422738.com | www.yh6878.com | www.898134.com | www.js7288.com | www.dao70.com | 5446kk.com | www.3933c.com | le888h.com | www.50080t.com | blr8033.com | www.61655q.com | hd7720.com | www.65707q.com | 3156fff.com | www.50732s.com | 8577z.cc | www.2632y.com | cp11993.com | www.sxyl4.com | www.45601.com | www.931518.com | www.x32126.cc | www.599643.com | www.83335k.com | www.32123u.com | www.538598.com | 2998i.com | www.1139356.com | 22205pj.com | www.38138a.com | 20188t.com | www.hg9388.com | 53262zz.com | www.80065h.com | bb8888-3.com | www.824879.com | www.7025q.com | sxrkrdjq12.com | www.hj358.com | p888888.com | www.91779a.com | uuu4255.com | www.4323g.com | bb5443.com | www.730631.com | www.pj5756.com | vs9777.com | www.e3065.com | 146030.com | www.68993272.com | 253504.com | www.797884.com | www.7636.com | 23233p.com | www.690510.com | wnsr828.com | www.33112.com | www.9374u.com | www.41518e.com | www.55526i.com | 1294i.cc | www.hd5388.com | www.3983139.com | www.239838.com | www.222505.com | 033x.net | www.03088.com | www.68666h.com | www.150957.com | www.tw7788.com | 37770795.com | www.50732s.com | www.lb9.com | 4997.com | www.xj6003.com | 11005b.com | www.585868.cc | www.944449.com | 88882007.com | www.26163a.com | www.9374r.com | 2535b.com | www.79095r.com | 88807w.com | www.548611.com | www.w75.com | 3530.com | www.gocp3.com | www.e3838.com | 30006z.com | www.77114p.com | www.87680c.com | 2381f.com | www.9422f.com | www.kb7070.com | 38345c.com | www.68365g.com | 44462949.com | 09244777.com | www.xpj33884.com | vip66656.com | 500000512.com | www.38775oo.com | 1654ww.com | z2894.com | www.am57877.com | www.hg0128.com | 7726yyy.com | www.16065w.com | www.88c07.com | 1654qq.com | www.78949l.com | www.hg6288.com | 336.cc | www.cai001.vip | www.hhvip87.com | yf2444.com | www.258031.com | www.35700b.com | sxpj62622.com | 239086.com | www.7004k.com | www.m222999.com | 4546.com | www.951912.com | www.1168p.com | 0747mm.com | sha0006.com | www.hg77704.com | www.29886h.com | hj4566com | www.fan73.com | www.85857.com | k2306.com | 5697emm.com | www.js02346.com | www.pj7991.com | 3467n.cc | www.346011.com | www.9895k.com | www.7720z.com | 4289e.com | www.cpyz1.com | www.cszb.com | js38886.com | 81366d.com | www.009ac.com | www.caipiao33c.com | 500000349.com | 1483mm.com | www.8199.cc | www.466587.com | 2017.net | 3189e.com | www.689066.com | www.06820v.com | www.v3309.com | 69111p.com | www.244343.com | www.55717c.com | www.532156.com | 88851r.com | 921710.com | www.43818l.com | www.751cp22.com | 463.am | 108143.cn | www.506257.com | www.p94600.com | www.946466.com | 0229422.com | blr6033.com | www.cp500.net | www.f32031.com | www.3941177.com | ddcp9.com | 67890ppp.com | www.hm3988.com | www.79095y.com | www.7770099.com | bb888822.com | 059j.cc | www.594277.com | www.4563.am | www.hg8270.com | 67629999.com | xhy000.com | c00351.com | www.27776.cc | www.513950.com | www.gf11888.com | 3434lll.com | 4288hh.com | www.175221.com | www.80075b.com | www.6776kk.com | www.7830x.com | 2127123.com | lehu80.com | www.195622.com | www.52072s.com | www.77vn777.com | www.4848p.com | 3121dd.com | 69441144.com | 071726.com | www.775706.com | www.4444bj.com | www.5099mm.com | www.7676760099.com | 2355h.com | 9646f.com | 818.cc | www.530995.com | www.76520x.com | www.678js222.com | www.9426.com | www.xpj8898.com | 6766bb.com | 2060044.com | love102.com | www.788464.com | www.bet353654.com | www.bet63m.com | www.44799.com | www.63877b.com | 77605s.com | 1294y.cc | 33318s.com | 6hcc44.com | www.912482.com | www.771493.com | www.85155.com | www.lygxs.com | www.35441777.com | 6701m.com | 91019d.com | 77ee940.com | 80031122.com | qq365g.com | www.601497.com | www.3416d.com | www.4331t.com | www.2021u.com | www.3846l.com | www.hxcp3.com | www.vns7777.cc | 87665i.com | 2146h.com | yhc998.com | 5856mm.com | 1077ss.com | 3522yy.com | www.501209.com | www.c5615.com | www.50080f.com | www.9996tt.com | www.j83377.com | www.38345j.com | www.6787749.com | www.5254y.com | www.zzzz0261.com | www.un5533.com | 3844uu.com | 2078y.com | 7811o.com | 4025l.com | 22207z.com | 53262o.com | 77605i.com | q2894.com | 2595u.com | jsok258.com | www.135125.com | www.503990.com | www.775710.com | www.c129.vip | www.07xyc.com | www.6832g.com | www.52072c.com | www.hg6767b.com | www.9422e.com | www.862239.com | www.7249w.com | www.196606.com | www.0012.com | www.14168j.com | www.8883066.com | www.377666z.com | www.45598q.com | www.1559508.com | www.357306.com | www.245885.com | www.2021j.com | www.n1432.com | www.a.pj3608.com | www.60886a.com | www.xpj11008.com | www.68365l.com | www.984703.com | www.535761.com | www.902cq.com | www.sx1833.com | www.7239f.com | www.77801l.com | www.50051r.com | www.3552n.com | www.hy5755.com | www.810526.com | www.579699.com | www.djcp234.com | www.003963.com | jl777777.com | 3679ii.com | c46.cc | 87578004.xyz | 3405rrr.com | 99306o.com | 88851o.com | 22556w.com | www.56733e.com | www.390722.com | www.3421n.com | www.448811.com | www.35252v.com | www.0011xpj.net | www.62979a.com | www.1466f.com | www.66332g.com | www.77czt.com | www.665039.com | www.053059.com | 1429t.com | 6063331.com | 1443e.com | hy738.com | 54443y.com | www.365815z.com | www.26yh.com | www.565560.com | www.g32031.com | www.xj112233.com | www.1222ac.com | www.505162.com | 6002400.com | feicai0371.com | 3435a.com | hh5443.com | www.1019993.com | www.tyc5955.com | www.601066.com | www.9464003.com | www.84499p.com | www.959581.com | www.50024o.com | zyrb.com.cn | 3482g.com | 649445.com | www.39695v.com | www.54555.com | www.932418.com | www.ky1004.com | www.927191.com | 1665ll.com | ll8159.cc | tz883.com | www.bjd333.com | www.883399u.com | www.57800d.com | www.hg366.com | www.965666.com | 3656lkk.com | 85698g.com | 28288ll.com | www.188gaidan.com | www.3171d.com | www.5446r.com | www.1035a.com | www.36166o.com | 82365v.com | 76886f.com | www.00829k.com | www.1343a.com | www.065815.com | www.949430.com | 9895o.com | 3726n.com | 84844001.com | www.662678.com | www.73990o.com | www.7793p.com | 58588.com | 5802ff.com | 4195xx.com | www.7811b.com | www.2544g3.com | www.022e.cc | 99111mm.com | 01234vvv.com | www.1113939.com | www.35252t.com | www.3155hd.com | www.303464.com | 4022xx.com | ff555w.com | www.500128.com | www.085993.com | www.663566.com | 70766622.com | 2418b.com | www.22gp.com | www.778306.com | www.763236.com | 55984c.com | 2934m.com | www.30440.com | www.5856869.com | www.354211.com | 83377r.com | www.033033c.com | www.u456x.com | www.61655m.com | es999.net | hbs124.com | www.6199b.com | www.y063801.com | www.817474.com | 9994cc8.com | 1156qq.com | www.cszb.com | www.7515aa.com | 1517726.com | 7989b.com | www.gd3658.com | www.83033w.com | 00787.com | tt6837.com | www.3814b.com | www.84499b.com | 9411xxx.com | 6118l.com | www.659200.com | www.77802j.com | 4195z.com | 56988b.com | www.370179.com | www.8839l.com | 6868qq.cc | 01266.com | www.9737cc.me | www.910424.com | xpj382.cn | www.67797r.com | www.8905e.com | www.126293.com | pj300.cc | www.636123.com | www.43818l.com | changlecai.com | www.ylhg4848.com | www.40598.com | www.309825.com | 32212z.com | www.46662.com | www.34788n.com | 22cc8331.com | www.38200v.com | www.v5995.com | www.66621i.com | xx7742.com | www.370179.com | www.976917.com | 348301.com | www.k87087.com | www.35918hh.com | 87665c.com | www.210zr.com | www.40288l.com | jianwei.com | jsjlb7.com | www.4996bx.com | www.327988.com | bet37566.com | www.848434.com | www.608850.com | 38850011.com | www.7759333.com | www.771501.com | 3308.com | www.sbtyc.com | www.745557.com | yyh917.com | www.68277111.com | www.706515.com | 34y35.com | www.11086.com | www.569380.com | 4182v.com | www.138578.com | www.317787.com | 2546y.com | www.56730.cc | 8827iii.com | www.yyhbet6.com | www.55676.com | betvictor98.com | www.g22365.com | www.73166j.com | 3983004.com | www.218003.com | www.926857.com | 7508d.com | www.4694x.com | www.77802i.com | 8790d.com | www.3691b.com | 22556l.com | www.98am444.com | www.5086k.com | 4488m.com | www.38345s.com | 68y68.com | www.284888.com | www.905647.com | 22117g.com | www.hg7739.com | www.535121.com | zz3189.com | www.55676l.com | 00774nn.com | www.567100.com | www.644680.com | 1077gg.com | www.hg860011.com | 19991p.com | www.1555789.com | www.555958.com | 4997n.com | www.ihg5599.com | 22274066.com | www.cntwsm.com | www.177542.com | www.hg55768.com | www.73166c.com | 6707888.com | www.sbd030.net | 18894.com | www.xinpujing888.vip | www.980996.com | dazhuangjia.me | www.48330p.com | 2709j.com | www.rycp157.com | 28758j.com | www.0860g.com | www.864255.com | 8742c.com | www.66653t.com | afcp09.com |